Atividade antifúngica da terapia fotodinâmica e própolis vermelha contra candida albicans: uma revisão de literatura

Abstract

The present study aims to conduct a narrative literature review on topics related to the antifungal activity of Candida albicans, a microorganism that inhabits the oral cavity. It is an opportunistic fungus present in the natural flora and has a high prevalence of infections. It is characterized by presenting various clinical forms, among those, the pseudomembranous stands out, the subject of this study. Thus, the present work seeks to gather studies that shows antifungal activity addressing the use of therapies using photodynamic light and a natural product based on red propolis. Photodynamic therapy as a low-power laser has an interaction mechanism between photosensitizers and low-intensity light sources, which will result in the development of reactive oxygen, which is toxic and works by generating oxidative damage to microorganisms. Therapy with the use of red propolis is also the objective of this study, it is a resinous compound present on the coast of northeastern Brazil that has been widely studied due to its complex chemical composition and diversity of biological activity, including the antimicrobial action. The red propolis has great potential to be used as an ally for the treatment of these fungal infections. From an academic point of view, the results of this investigation aim to contribute to a greater understanding of groups of risks for the development of C. albicans, and to include photodynamic therapy and the red propolis base as a support in the treatment for these infections and to promote new market solutions in the dental treatment field. [resumo fornecido pelo autor]