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Determinação da penetração prostática de clindamicina por microdiálise em ratos Wistar
(2021-03-23)
The prostatitis is considered a set of disease which assails the prostate, which can be caused by infectious microbial agents such pathogen evolved with the vulgar acne. This microorganism has been identified in prostatitis ...
Workflow científico de anotação genômica funcional e curadoria manual de genomas
(2021-04-07)
With the advent of new generation sequencing technologies, genome sequencing was no longer a scientific barrier. Analysing the structure and giving biological meaning to genomic and proteomic sequences in silico(genome ...
Avaliação das mutações em PI3K e do genótipo de HPV em pacientes com câncer cervical associados a desfechos clínicos e de sobrevida
(2021-06-30)
Objectives: To evaluate cervical cancer patients diagnosed and treated at an oncology reference institution and to analyze clinical and pathological features, survival outcomes, HPV genotype and PIK3CA mutation status; ...
Estratégias para o aproveitamento de ligninas de Eucalyptus globulus e de brácteas de Araucaria augustifolia para produção de insumos cosméticos para tratamento de hipercromias cutâneas
(2021-02-12)
There is a wide variety of cosmetics for hyperpigmentation treatments available on the market, however many are not as effective, causing adverse effects and harming the environment. For this reason, it is important to ...
Análise genômica de Penicillium echinulatum para predição de agrupamentos de genes envolvidos no metabolismo secundário
(2021-08)
Filamentous fungi are known for their importance in the production of secondary metabolites of interest: they are used in industry, in production of enzymes and drugs, in food, among other economically relevant compounds. ...
Análise de expressão diferencial de genes: uma solução computacional para identificação de biomarcadores de tumores gástricos em humanos
(2021-09-22)
Cancer is the second leading cause of death worldwide, with gastric cancer the third most fatal form of this disease. In this way, the present work aims to identify possible biomarkers in human gastric cancer tumors through ...
Estratégias de reuso de micélio de Penicillium echinulatum e de Trichoderma reesei em cultivo sólido para a produção de celulases e xilanases
(2021-12-02)
The usage of lignocellulosic biomass for second-generation ethanol production is the target of many studies in Biotechnology. One of the bottlenecks to the wide application of this technology lays on the difficulty of ...
Avaliação de marcadores de células progenitoras em cultura primária de células tumorais de câncer de mama
(2021-10-28)
Breast cancer (BC) includes different subtypes, among them Luminal A and B, HER2, and triple-negative. In all cases, cancer stem cells (CSC) seem to contribute to the development and progression of the disease and are ...