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Compostos de coordenação com zinco, ácido valproico, diclofenaco e ibuprofeno: uma nova abordagem para a obtenção de fármacos
(2020-08-21)
Non-steroidal anti-inflammatory drugs or NSAIDs ares the largest and most widespread class of drugs and as a consequence the largest representation of the drug market in history. NSAIDs act as inhibitors of the cyclooxygenase ...
Análise de regiões intergênicas de escherichia coli utilizando ferramentas computacionais
(2019-12-04)
Genes are segments of the deoxyribonucleic acid (DNA) molecule that contain information related to the metabolic functions necessary for the survival of an organism. Understanding the mechanisms that regulate gene expression ...
Characterization and annotation of archaeal promoter sequences
(2022-05-11)
Archaea were not long ago included as a particular domain in the tree of life. This vast and unexplored domain requires a plethora of techniques aimed to produce reliable inferences on it since not much information has ...
Valor preditivo de características clinico-patológicas e da expressão de genes de reparo do DNA na resposta à quimioterapia neoadjuvante em pacientes com câncer de mama
(2021-12-17)
Genome-wide analysis using microarrays has revolutionized the field of breast cancer (BC) research. A substantial body of evidence supports the clinical utilityof the 21-gene assay (Oncotype DX) and 70-gene assay (MammaPrint) ...